Trafficking of neuronal calcium channels

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F17%3A00485451" target="_blank" >RIV/61388963:_____/17:00485451 - isvavai.cz</a>

Result on the web

<a href="http://www.neuronalsignaling.org/content/1/1/NS20160003" target="_blank" >http://www.neuronalsignaling.org/content/1/1/NS20160003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1042/NS20160003" target="_blank" >10.1042/NS20160003</a>

Result language

angličtina

Original language name

Trafficking of neuronal calcium channels

Original language description

Neuronal voltage-gated calcium channels (VGCCs) serve complex yet essential physiological functions via their pivotal role in translating electrical signals into intracellular calcium elevations and associated downstream signalling pathways. There are a number of regulatory mechanisms to ensure a dynamic control of the number of channels embedded in the plasma membrane, whereas alteration of the surface expression of VGCCs has been linked to various disease conditions. Here, we provide an overview of the mechanisms that control the trafficking of VGCCs to and from the plasma membrane, and discuss their implication in pathophysiological conditions and their potential as therapeutic targets.

Czech name

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Czech description

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Type

J_ost - Miscellaneous article in a specialist periodical

CEP classification

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OECD FORD branch

30105 - Physiology (including cytology)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuronal Signaling

ISSN

2059-6553

e-ISSN

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Volume of the periodical

1

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

16

Pages from-to

NS20160003

UT code for WoS article

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EID of the result in the Scopus database

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