New Phosphine Ligand Architectures Lead to Efficient Gold Catalysts for Cycloisomerization Reactions at Very Low Loading
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F18%3A00498623" target="_blank" >RIV/61388963:_____/18:00498623 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/18:10383123
Result on the web
<a href="http://dx.doi.org/10.1002/adsc.201800938" target="_blank" >http://dx.doi.org/10.1002/adsc.201800938</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/adsc.201800938" target="_blank" >10.1002/adsc.201800938</a>
Alternative languages
Result language
angličtina
Original language name
New Phosphine Ligand Architectures Lead to Efficient Gold Catalysts for Cycloisomerization Reactions at Very Low Loading
Original language description
A simple and efficient access to a new P-chiral, but so far racemic ligand class featuring ortho-trityl and ortho-biaryl motifs is reported. The phosphines are prepared by efficient three- to four-step modular syntheses from simple branched alkyl(diphenyl)phosphine oxides in 52-63% overall yield. They form stable gold complexes, which were characterized by X-ray crystallography and spectroscopic methods. Fundamental catalytic properties of the complexes were studied in 1,6-enyne cycloisomerization reactions of achiral substrates to benchmark their activity against the efficient achiral catalyst (JohnPhos)AuCl. The results show that the new complexes can be applied in amounts down to 100 ppm allowing the cycloisomerization reactions to be performed with turnover frequencies of 20000 h(-1) and turnover numbers of up to 10000 h(-1).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Advanced Synthesis & Catalysis
ISSN
1615-4150
e-ISSN
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Volume of the periodical
360
Issue of the periodical within the volume
21
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
4215-4224
UT code for WoS article
000449688000027
EID of the result in the Scopus database
2-s2.0-85053889970