Macromolecular conjugates for visualization and separation of proteins and cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F18%3A00518013" target="_blank" >RIV/61388963:_____/18:00518013 - isvavai.cz</a>
Alternative codes found
RIV/61389013:_____/18:00518013 RIV/00216208:11310/18:10409444
Result on the web
<a href="https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20181129&DB=&locale=en_EP&CC=AU&NR=2016207126B2&KC=B2&ND=5#" target="_blank" >https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20181129&DB=&locale=en_EP&CC=AU&NR=2016207126B2&KC=B2&ND=5#</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Macromolecular conjugates for visualization and separation of proteins and cells
Original language description
Macromolecular conjugates for visualization and separation of proteins and cells The present invention descripbes macromolecular water-soluble conjugates based on synthetic copolymers to which at least one affinity tag, at least one imaging probe and at least one targeting ligand are bound via covalent bonds. The macromolecular conjugate may be used in identification, visualization, quantification or isolation of proteins and/or cells both in vitro and in vivo. HPMA copolymer, i.e.poly(HPMA-co-Ma-β-Ala-TT), copolymer prepared by conventional solution radical polymerization or controlled radical copolymerization (e.g. RAFT copolymerization, reversible addition-fragmentation chain-transfer) of N-(2- hydroxypropyl)methacrylamide (HPMA) and 3-(3-methakrylamidopropanoyl)thiazolidine-2-thione (Ma-P-Ala-TT) can be preferably used as the basic copolymer.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
AU2016207126
Publisher
AU001 -
Publisher name
IP Australia
Place of publication
Phillip ACT
Publication country
AU - AUSTRALIA
Date of acceptance
Nov 29, 2018
Owner name
Ústav organické chemie a biochemie AV ČR, v. v. i. - Ústav makromolekulární chemie AV ČR, v. v. i. - Univerzita Karlova v Praze
Method of use
B - Výsledek je využíván orgány státní nebo veřejné správy
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence