Macromolecular conjugates for visualization and separation of proteins and cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F19%3A00518015" target="_blank" >RIV/61388963:_____/19:00518015 - isvavai.cz</a>
Alternative codes found
RIV/61389013:_____/19:00518015 RIV/00216208:11310/19:10409447
Result on the web
<a href="https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20190806&DB=&locale=en_EP&CC=CA&NR=2970913C&KC=C&ND=7#" target="_blank" >https://worldwide.espacenet.com/publicationDetails/originalDocument?FT=D&date=20190806&DB=&locale=en_EP&CC=CA&NR=2970913C&KC=C&ND=7#</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Macromolecular conjugates for visualization and separation of proteins and cells
Original language description
Macromolecular conjugates for visualization and separation of proteins and cells The present invention descripbes macromolecular water-soluble conjugates based on synthetic copolymers to which at least one affinity tag, at least one imaging probe and at least one targeting ligand are bound via covalent bonds. The macromolecular conjugate may be used in identification, visualization, quantification or isolation of proteins and/or cells both in vitro and in vivo. HPMA copolymer, i.e.poly(HPMA-co-Ma-ß-Ala-TT), copolymer prepared by conventional solution radical polymerization or controlled radical copolymerization (e.g. RAFT copolymerization, reversible addition-fragmentation chain-transfer) of N-(2- hydroxypropyl)methacrylamide (HPMA) and 3-(3-methakrylamidopropanoyl)thiazolidine-2-thione (Ma-P-Ala-TT) can be preferably used as the basic copolymer.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Patent/design ID
CA2970913
Publisher
CA001 -
Publisher name
Canadian Intellectual Property Office (CIPO)
Place of publication
Gatineau, Québec
Publication country
CA - CANADA
Date of acceptance
Aug 6, 2019
Owner name
Ústav organické chemie a biochemie AV ČR, v. v. i. - Ústav makromolekulární chemie AV ČR, v. v. i. - Univerzita Karlova v Praze
Method of use
B - Výsledek je využíván orgány státní nebo veřejné správy
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence

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