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A New Insight into the Stereoelectronic Control of the Pd-0-Catalyzed Allylic Substitution: Application for the Synthesis of Multisubstituted Pyran-2-ones via an Unusual 1,3-Transposition

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F19%3A00507868" target="_blank" >RIV/61388963:_____/19:00507868 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11160/19:10396875 RIV/00216208:11310/19:10396875

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201900323" target="_blank" >https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201900323</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/chem.201900323" target="_blank" >10.1002/chem.201900323</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    A New Insight into the Stereoelectronic Control of the Pd-0-Catalyzed Allylic Substitution: Application for the Synthesis of Multisubstituted Pyran-2-ones via an Unusual 1,3-Transposition

  • Original language description

    Pyran-2-ones 3 undergo a novel Pd-0-catalyzed 1,3-rearrangement to afford isomers 6. The reaction proceeds via an eta(2)-Pd complex, the pyramidalization of which (confirmed by quantum chemistry calculations) offers a favorable antiperiplanar alignment of the Pd-C and allylic C-O bonds (C), thus allowing the formation of an eta(3)-Pd intermediate. Subsequent rotation and rate-limiting recombination with the carboxylate arm then gives isomeric pyran-2-ones 6. The calculated free energies reproduce the observed kinetics semi-quantitatively.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10403 - Physical chemistry

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemistry - A European Journal

  • ISSN

    0947-6539

  • e-ISSN

  • Volume of the periodical

    25

  • Issue of the periodical within the volume

    34

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    8

  • Pages from-to

    8053-8060

  • UT code for WoS article

    000474807200014

  • EID of the result in the Scopus database

    2-s2.0-85065641205