Prolactin-releasing peptide: Physiological and pharmacological properties
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F19%3A00511196" target="_blank" >RIV/61388963:_____/19:00511196 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/19:00517566
Result on the web
<a href="https://www.mdpi.com/1422-0067/20/21/5297" target="_blank" >https://www.mdpi.com/1422-0067/20/21/5297</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms20215297" target="_blank" >10.3390/ijms20215297</a>
Alternative languages
Result language
angličtina
Original language name
Prolactin-releasing peptide: Physiological and pharmacological properties
Original language description
Prolactin-releasing peptide (PrRP) belongs to the large RF-amide neuropeptide family with a conserved Arg-Phe-amide motif at the C-terminus. PrRP plays a main role in the regulation of food intake and energy expenditure. This review focuses not only on the physiological functions of PrRP, but also on its pharmacological properties and the actions of its G-protein coupled receptor, GPR10. Special attention is paid to structure-activity relationship studies on PrRP and its analogs as well as to their effect on different physiological functions, mainly their anorexigenic and neuroprotective features and the regulation of the cardiovascular system, pain, and stress. Additionally, the therapeutic potential of this peptide and its analogs is explored.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/GA18-10591S" target="_blank" >GA18-10591S: Lipidized analogs of prolactin-releasing peptide as potential agents for obesity therapy: search for mechanism of action</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Molecular Sciences
ISSN
1422-0067
e-ISSN
—
Volume of the periodical
20
Issue of the periodical within the volume
21
Country of publishing house
CH - SWITZERLAND
Number of pages
22
Pages from-to
5297
UT code for WoS article
000498946100055
EID of the result in the Scopus database
2-s2.0-85074170230