Evaluation of silica from different vendors as the solid support of anion-exchange chiral stationary phases by means of preferential sorption and liquid chromatography.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F19%3A00511718" target="_blank" >RIV/61388963:_____/19:00511718 - isvavai.cz</a>

Alternative codes found

RIV/67985858:_____/19:00511718 RIV/60461373:22310/19:43919053 RIV/60461373:22340/19:43919053

Result on the web

<a href="http://hdl.handle.net/11104/0303439" target="_blank" >http://hdl.handle.net/11104/0303439</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jssc.201900731" target="_blank" >10.1002/jssc.201900731</a>

Result language

angličtina

Original language name

Evaluation of silica from different vendors as the solid support of anion-exchange chiral stationary phases by means of preferential sorption and liquid chromatography.

Original language description

Chromatographic performance of a chiral stationary phase is significantly influenced by the employed solid support. Properties of the most commonly used support, silica particles, such as size and size distribution, and pore size are of utmost importance for both superficially porous particles and fully porous particles. In this work, we have focused on evaluation of fully porous particles from three different vendors as solid supports for a brush-type chiral stationary phase based on 9-O-tert-butylcarbamoyl quinidine. We have prepared corresponding stationary phases under identical experimental conditions and determined the parameters of the modified silica by physisorption measurements and scanning electron microscopy. Enantiorecognition properties of the chiral stationary phases have been studied using preferential sorption experiments. The same material was slurry-packed into chromatographic columns and the chromatographic properties have been evaluated in liquid chromatography. We show that preferential sorption can provide valuable information about the influence of the pore size and total pore volume on the interaction of analytes of different size with the chirally-modified silica surface. The data can be used to understand differences observed in chromatographic evaluation of the chiral stationary phases. The combination of preferential sorption and liquid chromatography separation can provide detailed information on new chiral stationary phases.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

<a href="/en/project/GA17-00089S" target="_blank" >GA17-00089S: Separation of Racemic Mixtures by Membrane Processes</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Separation Science

ISSN

1615-9306

e-ISSN

—

Volume of the periodical

42

Issue of the periodical within the volume

24

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

3653-3661

UT code for WoS article

000493821900001

EID of the result in the Scopus database

2-s2.0-85074777197