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Cyclodextrin-based transporter of nucleoside triphosphate transporter across the cell membrane, its preparation and use

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F19%3A00519507" target="_blank" >RIV/61388963:_____/19:00519507 - isvavai.cz</a>

  • Result on the web

    <a href="https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=EP&NR=3402839B1&KC=B1&FT=D&ND=4&date=20190529&DB=&locale=en_EP#" target="_blank" >https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=EP&NR=3402839B1&KC=B1&FT=D&ND=4&date=20190529&DB=&locale=en_EP#</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cyclodextrin-based transporter of nucleoside triphosphate transporter across the cell membrane, its preparation and use

  • Original language description

    Compounds of general formula 6 and 13 where X is -NH-C(NH2)=N+H2 or -N+H3, Y is a linear oligomer consisting of arginine units terminated with an aminodimethylenamide unit (-Arg)n-NH-(CH2)2-NH2, where n = 6-10, or arginine-aminocaproic units (-Arg-Aca)n- NH2, where n = 6 to 10, A- = CF3COO- or C1- and m = 1-2. Preparation and use of compounds of general formula 6 and 13 as carriers of nucleoside triphosphates across the cell membranes for the purpose of incorporation of modified nucleoside triphosphates into the cellular DNA or RNA. Use of compounds of general formula 6 and 13 as carriers of nucleoside triphosphates across the cell membrane for the purpose of determining the virostatic activities of modified nucleoside triphosphates. Use of compounds of general formula 6 and 13 as carriers of modified nucleoside triphosphates across the cell membrane for the purpose of determining cell proliferation and S phase of the cell cycle.

  • Czech name

  • Czech description

Classification

  • Type

    P - Patent

  • CEP classification

  • OECD FORD branch

    10401 - Organic chemistry

Result continuities

  • Project

    <a href="/en/project/GA17-14791S" target="_blank" >GA17-14791S: Synthetic analogues of nucleoside triphosphate transporters: development and applications</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Patent/design ID

    EP3402839

  • Publisher

    EPO_1 -

  • Publisher name

    European Patent Office

  • Place of publication

    Munich, The Hague, Berlin, Vienna, Brussels

  • Publication country

  • Date of acceptance

    May 29, 2019

  • Owner name

    Ústav organické chemie a biochemie AV ČR, v. v. i

  • Method of use

    B - Výsledek je využíván orgány státní nebo veřejné správy

  • Usage type

    A - K využití výsledku jiným subjektem je vždy nutné nabytí licence