Cyclodextrin-based transporter of nucleoside triphosphate transporter across the cell membrane, its preparation and use
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F21%3A00552741" target="_blank" >RIV/61388963:_____/21:00552741 - isvavai.cz</a>
Result on the web
<a href="https://worldwide.espacenet.com/patent/search/family/058410055/publication/US11168153B2?q=US11168153" target="_blank" >https://worldwide.espacenet.com/patent/search/family/058410055/publication/US11168153B2?q=US11168153</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Cyclodextrin-based transporter of nucleoside triphosphate transporter across the cell membrane, its preparation and use
Original language description
Compounds of general formulae 6 and 13 where X is —NH—C(NH2)═N+H2 or —N+H3, Y is a linear oligomer of arginine units terminated with an aminodimethylenamide unit (-Arg)n-NH—(CH2)2—NH2, where n=6-10, or arginine-aminocaproic units (-Arg-Aca)n-NH2, where n=6 to 10, A-═CF3COO— or Cl— and m=1-2. Preparation and use of compounds of general formula 6 and 13 as carriers of nucleoside triphosphates across the cell membranes for the purpose of incorporation of modified nucleoside triphosphates into cellular DNA or RNA. Use of compounds of general formula 6 and 13 as carriers of nucleoside triphosphates across the cell membrane for determining the virostatic activities of modified nucleoside triphosphates. Use of compounds of general formula 6 and 13 as carriers of modified nucleoside triphosphates across the cell membrane for determining cell proliferation and S phase of the cell cycle.
Czech name
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Czech description
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Classification
Type
P - Patent
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
<a href="/en/project/GA17-14791S" target="_blank" >GA17-14791S: Synthetic analogues of nucleoside triphosphate transporters: development and applications</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Patent/design ID
US11168153
Publisher
US001 -
Publisher name
United States Patent and Trademark Office (USPTO)
Place of publication
Alexandria
Publication country
US - UNITED STATES
Date of acceptance
Nov 9, 2021
Owner name
Ústav organické chemie a biochemie AV ČR, v. v. i
Method of use
B - Výsledek je využíván orgány státní nebo veřejné správy
Usage type
A - K využití výsledku jiným subjektem je vždy nutné nabytí licence