Using Polymers to Enhance the Carbon Nanomaterial Biointerface

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F19%3A00521416" target="_blank" >RIV/61388963:_____/19:00521416 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/9781119373476.ch2" target="_blank" >http://dx.doi.org/10.1002/9781119373476.ch2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/9781119373476.ch2" target="_blank" >10.1002/9781119373476.ch2</a>

Result language
angličtina
Original language name
Using Polymers to Enhance the Carbon Nanomaterial Biointerface
Original language description
This chapter focuses on functionalization of carbon nanomaterials (CNMs) with polymers for biomedical applications. A classical theoretical approach based on Derjaguin‐Landau‐Verwey‐Overbeek (DLVO) theory is commonly used to predict the stability of a colloidal system. CNMs can be functionalized with polymers via two types of approaches: noncovalent coating and covalent modification. The physicochemical properties of CNMs are determined by their intrinsic nanostructure. The chapter discusses the effect of polymer functionalization on the spectral properties of various CNMs. Stimuli‐responsive polymers respond to their environment by changing their physical and/or chemical properties. Among stimuli‐responsive polymers, thermoresponsive polymers have been exploited most abundantly to modify carbon nanoparticles. The development of nonviral, nonimmunogenic, and biocompatible vectors for efficient intracellular transfection of nucleic acids (NAs) is one of the challenges facing future gene therapy approaches. The surface of the CNMs can be functionalized by covalent or noncovalent attachment of macromolecular layers to create reliable nonviral gene delivery vectors.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy
ISBN
978-1-119-37345-2
Number of pages of the result
28
Pages from-to
15-42
Number of pages of the book
376
Publisher name
Wiley
Place of publication
Hoboken
UT code for WoS chapter
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