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Saturation Transfer Difference NMR Spectroscopy for the Elucidation of Supramolecular Albumin-Polymer Interactions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F21%3A00543855" target="_blank" >RIV/61388963:_____/21:00543855 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1021/acsmacrolett.1c00270" target="_blank" >https://doi.org/10.1021/acsmacrolett.1c00270</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1021/acsmacrolett.1c00270" target="_blank" >10.1021/acsmacrolett.1c00270</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Saturation Transfer Difference NMR Spectroscopy for the Elucidation of Supramolecular Albumin-Polymer Interactions

  • Original language description

    Albumin has consistently demonstrated its potential for enhancing the delivery of drugs and polymer–drug conjugates, binding via supramolecular forces within its multiple binding sites. Herein, we introduce saturation transfer difference (STD-NMR) as a method to identify the interactions between a polymer library and bovine serum albumin (BSA). With STD-NMR, the binding ability of polymers can be quickly screened by focusing on their individual structural features, making this technique more suitable for high throughput screening in comparison to traditional fluorescence studies.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10401 - Organic chemistry

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    ACS Macro Letters

  • ISSN

    2161-1653

  • e-ISSN

    2161-1653

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    819-824

  • UT code for WoS article

    000677482700009

  • EID of the result in the Scopus database

    2-s2.0-85109335557