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Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00567543" target="_blank" >RIV/61388963:_____/23:00567543 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985823:_____/23:00567543

  • Result on the web

    <a href="https://doi.org/10.3390/ijms24010507" target="_blank" >https://doi.org/10.3390/ijms24010507</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/ijms24010507" target="_blank" >10.3390/ijms24010507</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids

  • Original language description

    Muscarinic acetylcholine receptors expressed in the central nervous system mediate various functions, including cognition, memory, or reward. Therefore, muscarinic receptors represent potential pharmacological targets for various diseases and conditions, such as Alzheimer's disease, schizophrenia, addiction, epilepsy, or depression. Muscarinic receptors are allosterically modulated by neurosteroids and steroid hormones at physiologically relevant concentrations. In this review, we focus on the modulation of muscarinic receptors by neurosteroids and steroid hormones in the context of diseases and disorders of the central nervous system. Further, we propose the potential use of neuroactive steroids in the development of pharmacotherapeutics for these diseases and conditions.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

    <a href="/en/project/LX22NPO5107" target="_blank" >LX22NPO5107: National institute for Neurological Research</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Molecular Sciences

  • ISSN

    1422-0067

  • e-ISSN

    1422-0067

  • Volume of the periodical

    24

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    27

  • Pages from-to

    507

  • UT code for WoS article

    000910252100001

  • EID of the result in the Scopus database

    2-s2.0-85146017615