Galectin-targeting glycocalix[4]arenes can enter the cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00575861" target="_blank" >RIV/61388963:_____/23:00575861 - isvavai.cz</a>
Alternative codes found
RIV/61388971:_____/23:00575861 RIV/68407700:21460/23:00373272 RIV/00216208:11310/23:10472975 RIV/60461373:22310/23:43927779 RIV/60461373:22330/23:43927779
Result on the web
<a href="https://pubs.rsc.org/en/content/articlelanding/2023/CC/D3CC02905K" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2023/CC/D3CC02905K</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/d3cc02905k" target="_blank" >10.1039/d3cc02905k</a>

Result language
angličtina
Original language name
Galectin-targeting glycocalix[4]arenes can enter the cells
Original language description
Elevated levels of galectin-3 are associated with tumorigenesis. Its inhibition with high-affinity carbohydrate ligands opens new therapeutic routes. Targeting of intracellular galectin-3 is challenging for polar inhibitors like carbohydrates. We demonstrate the potential of novel biomedical research tools, glycocalix[4]arenes, to enter epithelial cells, which may allow their interaction with galectin-3.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry

Project
<a href="/en/project/GA22-00317S" target="_blank" >GA22-00317S: Galectin-3 as a target molecule for the reversal of vascular remodelling in hypoxic pulmonary hypertension</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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