Transforming parasites into their own foes: parasitic extracellular vesicles as a vaccine platform

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00576245" target="_blank" >RIV/61388963:_____/23:00576245 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.pt.2023.08.009" target="_blank" >https://doi.org/10.1016/j.pt.2023.08.009</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.pt.2023.08.009" target="_blank" >10.1016/j.pt.2023.08.009</a>

Result language
angličtina
Original language name
Transforming parasites into their own foes: parasitic extracellular vesicles as a vaccine platform
Original language description
Parasitic diseases continue to afflict millions of people globally. However, traditional vaccine development strategies are often difficult to apply to parasites, leaving an immense unmet need for new effective vaccines for the prevention and control of parasitic infections. As parasites commonly use extracellular vesicles (EVs) to interact with, interfere with, or modulate the host immune response from a distance, parasite-derived EVs may provide promising vaccine agents that induce immunity against parasitic infections. We here present achievements to date and the challenges and limitations associated with using parasitic EVs in a clinical context. Despite the many difficulties that need to be overcome, we believe this direction could offer a new and reliable source of therapeutics for various neglected parasitic diseases.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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