From the outer ear to the nerve: A complete computer model of the peripheral auditory system

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00577750" target="_blank" >RIV/61388963:_____/23:00577750 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.heares.2023.108900" target="_blank" >https://doi.org/10.1016/j.heares.2023.108900</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.heares.2023.108900" target="_blank" >10.1016/j.heares.2023.108900</a>

Result language
angličtina
Original language name
From the outer ear to the nerve: A complete computer model of the peripheral auditory system
Original language description
Computer models of the individual components of the peripheral auditory system – the outer, middle, and inner ears and the auditory nerve – have been developed in the past, with varying level of detail, breadth, and faithfulness of the underlying parameters. Building on previous work, we advance the modeling of the ear by presenting a complete, physiologically justified, bottom-up computer model based on up-to-date experimental data that integrates all of these parts together seamlessly. The detailed bottom-up design of the present model allows for the investigation of partial hearing mechanisms and their defects, including genetic, molecular, and microscopic factors. Also, thanks to the completeness of the model, one can study microscopic effects in the context of their implications on hearing as a whole, enabling the correlation with neural recordings and non-invasive psychoacoustic methods. Such a model is instrumental for advancing quantitative understanding of the mechanism of hearing, for investigating various forms of hearing impairment, as well as for devising next generation hearing aids and cochlear implants.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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