Structure and inhibition of monkeypox virus methyltransferase VP39

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F23%3A00578951" target="_blank" >RIV/61388963:_____/23:00578951 - isvavai.cz</a>
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/41/75" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/41/75</a>
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Structure and inhibition of monkeypox virus methyltransferase VP39
Original language description
Monkeypox is a zoonotic disease with pandemic potential. It is caused by the monkeypox virus (MPXV), adouble-stranded DNA virus from the Poxviridae family. MPXV replicates in cytoplasm and thus, it must encode for the DNA/RNA replication machinery. Besides the DNA-dependent DNA and RNA polymerases, it also encodes for the RNA capping enzymes. In poxviruses, the RNA cap is crucial for the translation and stability of viral RNA and for immune evasion. One of the key components of the monkeypox virus RNA capping machinery is the RNA methyltransferase (MTase) VP39.
Czech name
—
Czech description
—

Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)