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Induced Chirality in Canthaxanthin Aggregates Reveals Multiple Levels of Supramolecular Organization

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F24%3A00585610" target="_blank" >RIV/61388963:_____/24:00585610 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1002/anie.202402449" target="_blank" >https://doi.org/10.1002/anie.202402449</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/anie.202402449" target="_blank" >10.1002/anie.202402449</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Induced Chirality in Canthaxanthin Aggregates Reveals Multiple Levels of Supramolecular Organization

  • Original language description

    Carotenoids tend to form supramolecular aggregates via non-covalent interactions where the chirality of individual molecules is amplified to the macroscopic level. We show that this can also be achieved for non-chiral carotenoid monomers interacting with polysaccharides. The chirality induction in canthaxanthin (CAX), caused by heparin (HP) and hyaluronic acid (HA), was monitored by chiroptical spectroscopy. Electronic circular dichroism (ECD) and Raman optical activity (ROA) spectra indicated the presence of multiple carotenoid formations, such as H- and J-type aggregates. This is consistent with molecular dynamics (MD) and density functional theory (DFT) simulations of the supramolecular structures and their spectroscopic response.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10403 - Physical chemistry

Result continuities

  • Project

    <a href="/en/project/GA22-04669S" target="_blank" >GA22-04669S: Sensitivity Enhancement of Vibrational Optical Activity Spectroscopy for Biomolecules</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Angewandte Chemie - International Edition

  • ISSN

    1433-7851

  • e-ISSN

    1521-3773

  • Volume of the periodical

    63

  • Issue of the periodical within the volume

    21

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    7

  • Pages from-to

    e202402449

  • UT code for WoS article

    001200660800001

  • EID of the result in the Scopus database

    2-s2.0-85190129987