HIV-1 uncoating and beyond
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F24%3A00599889" target="_blank" >RIV/61388963:_____/24:00599889 - isvavai.cz</a>
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/48/87" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/48/87</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
HIV-1 uncoating and beyond
Original language description
Human immunodeficiency virus type 1 (HIV-1) is an enveloped retrovirus responsible for the global AIDS pandemic. Within the virion lies a conical core containing two copies of single-stranded positive-sense genomic RNA. Upon entry into a host cell through membrane fusion, the RNA genome is reverse transcribed into viral double-stranded DNA (vDNA). This vDNA is then imported into the nucleus and integrated into the host genome, establishing a permanent infection. HIV-1 can infect non-dividing cells, necessitating mechanisms to traverse the nuclear membrane without compromising its integrity.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů