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A universal language for finding mass spectrometry data patterns

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F25%3A00619770" target="_blank" >RIV/61388963:_____/25:00619770 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1038/s41592-025-02660-z" target="_blank" >https://doi.org/10.1038/s41592-025-02660-z</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s41592-025-02660-z" target="_blank" >10.1038/s41592-025-02660-z</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    A universal language for finding mass spectrometry data patterns

  • Original language description

    Despite being information rich, the vast majority of untargeted mass spectrometry data are underutilized, most analytes are not used for downstream interpretation or reanalysis after publication. The inability to dive into these rich raw mass spectrometry datasets is due to the limited flexibility and scalability of existing software tools. Here we introduce a new language, the Mass Spectrometry Query Language (MassQL), and an accompanying software ecosystem that addresses these issues by enabling the community to directly query mass spectrometry data with an expressive set of user-defined mass spectrometry patterns. Illustrated by real-world examples, MassQL provides a data-driven definition of chemical diversity by enabling the reanalysis of all public untargeted metabolomics data, empowering scientists across many disciplines to make new discoveries. MassQL has been widely implemented in multiple open-source and commercial mass spectrometry analysis tools, which enhances the ability, interoperability and reproducibility of mining of mass spectrometry data for the research community.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nature Methods

  • ISSN

    1548-7091

  • e-ISSN

    1548-7105

  • Volume of the periodical

    22

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    1247-1254

  • UT code for WoS article

    001485547200001

  • EID of the result in the Scopus database

    2-s2.0-105004840486