Salivary gland extract from Ixodes ricinus tick polarizes the cytokine profile toward th2 and suppresses proliferation of T lymphocytes in human pbmc culture.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F01%3A53014015" target="_blank" >RIV/61388971:_____/01:53014015 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Salivary gland extract from Ixodes ricinus tick polarizes the cytokine profile toward th2 and suppresses proliferation of T lymphocytes in human pbmc culture.

Original language description

Tick salivary gland extract (SGE) was previously shown to inhibit murine T cell proliferation. In mice, SGE has an inhibitory effect on Thl and a stimulatory effect on Th2 cytokine elaboration. In the present study, tick-mediated immunomodulation of human T cell proliferation and cytokine elaboration has analyzed using human peripheral blood mononuclear cells.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Parasitology

ISSN

0022-3395

e-ISSN

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Volume of the periodical

87

Issue of the periodical within the volume

6

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

1342-1348

UT code for WoS article

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EID of the result in the Scopus database

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