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Therapeutic polymer conjugates Poly-L-glutamic acid paclitaxel and glycine-camptothecin

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F04%3A00107935" target="_blank" >RIV/61388971:_____/04:00107935 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Therapeutic polymer conjugates Poly-L-glutamic acid paclitaxel and glycine-camptothecin

  • Original language description

    Poly-L-glutamic acid bearing cytostatic drug paclitaxel is well tolerated by organism, demonstrates enhanced accumulation in tumors and is currently under evaluation in phase II trials in solid tumors and phase II trials for ovary and NSCLC. Poly-L-glutamic acid bearing cytostatic drug camptothecin is also well tolerated and easily administered and was recomended for further clinical developmant and phase I/II of clinical trials.

  • Czech name

    Terapeutické polymerní konjugáty poly-L-glutamové kyseliny a glycin-camptothecinu

  • Czech description

    Poly-L-glutamát nesoucí cytostatikum paclitaxel je velmi dobře tolerovaný organismem, vykazuje zvýšenou akumulaci v nádoru a prochází fází II preklinických studií pro solidní nádory a fází III pro ovariální karcinomy a NSCLC. Konjugát poly-L-glutamátu acamptothecinem je také velmi dobře tolerovaný a snadno aplikovatelný a byl doporučen pro fázi I/II preklinických testů.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    IDrugs

  • ISSN

    1369-7056

  • e-ISSN

  • Volume of the periodical

    7

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    4

  • Pages from-to

    114-117

  • UT code for WoS article

  • EID of the result in the Scopus database