Distribution and development of the postnatal murine V delta 1 T-cell receptor repertoire
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F10%3A00352860" target="_blank" >RIV/61388971:_____/10:00352860 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Distribution and development of the postnatal murine V delta 1 T-cell receptor repertoire
Original language description
Murine gamma/delta T cells express canonical V gamma 5V delta 1 chains in the epidermis and V gamma 6V delta 1 chains at reproductive sites. Both subsets carry an identical V delta 1-D delta 2-J delta 2 chain which completely lacks junctional diversity.These cells are thought to monitor tissue integrity via recognition of stress-induced self antigens. In this study, we showed by reverse transcription-polymerase chain reaction (RT-PCR), complementarity determining region 3 (CDR3) spectratyping and sequencing of the junctional regions of V delta 1 chains from C57BL/6 mice (aged 1 day to 14 months) that the canonical V delta 1-D delta 2-J delta 2 chain is also consistently present at other sites such as the thymus, gut, lung, liver, spleen and peripheralblood
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA524%2F07%2F0087" target="_blank" >GA524/07/0087: Development of peripheral gamma delta T lymhocytes in swine</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Immunology
ISSN
0019-2805
e-ISSN
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Volume of the periodical
131
Issue of the periodical within the volume
2
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
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UT code for WoS article
000281554600005
EID of the result in the Scopus database
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