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EN
ČeštinaEnglish

Alarmin HMGB1 is released in the small intestine of gnotobiotic piglets infected with enteric pathogens and its level in plasma reflects severity of sepsis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F11%3A00369569" target="_blank" >RIV/61388971:_____/11:00369569 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s10875-010-9505-3" target="_blank" >http://dx.doi.org/10.1007/s10875-010-9505-3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s10875-010-9505-3" target="_blank" >10.1007/s10875-010-9505-3</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Alarmin HMGB1 is released in the small intestine of gnotobiotic piglets infected with enteric pathogens and its level in plasma reflects severity of sepsis

  • Original language description

    High mobility group box 1 (HMGB1) is essential for correct DNA folding and transcription and can be released from damaged cells or secreted by stimulated cells. One-week-old germ-free piglets were orally infected/colonized with enteric bacterial pathogens (Salmonella Typhimurium or Escherichia coli O55) or with probiotic bacteria (E. coli Nissle 1917) for 24 h. The local and systemic expression of HMGB1 is a suitable marker of severity of sepsis in the gnotobiotic piglet infection model

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

    —

Result continuities

  • Project

    <a href="/en/project/ME%20915" target="_blank" >ME 915: Induction of antimicrobial peptides in Salmonella-caused gastroenteritis in dependence on type of lipopolysacharide</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Clinical Immunology

  • ISSN

    0271-9142

  • e-ISSN

    —

  • Volume of the periodical

    31

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    488-497

  • UT code for WoS article

    000292556000022

  • EID of the result in the Scopus database

    —

Similar results(10)

High Mobility Group Box 1 and TLR4 Signaling Pathway in Gnotobiotic Piglets Colonized/Infected with L. amylovorus, L. mucosae, E. coli Nissle 1917 and S. Typhimurium.High mobility group box 1 and TLR4 signaling pathway in gnotobiotic piglets colonized/infected with L. amylovorus, L. mucosae, E. coli Nissle 1917 and S. typhimuriumHigh Mobility Group Box 1 and TLR4 Signaling Pathway in Gnotobiotic Piglets Colonized/Infected with L. amylovorus, L. mucosae, E. coli Nissle 1917 and S. Typhimurium.