Effect of starter unit availability on the spectrum of manumycin-type metabolites produced by Streptomyces nodosus ssp asukaensis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F11%3A00370935" target="_blank" >RIV/61388971:_____/11:00370935 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/j.1365-2672.2011.05132.x" target="_blank" >http://dx.doi.org/10.1111/j.1365-2672.2011.05132.x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1365-2672.2011.05132.x" target="_blank" >10.1111/j.1365-2672.2011.05132.x</a>

Result language
angličtina
Original language name
Effect of starter unit availability on the spectrum of manumycin-type metabolites produced by Streptomyces nodosus ssp asukaensis
Original language description
Production of minor asukamycin congeners and its new derivatives by combination of targeted genetic manipulations with specific precursor feeding in the producer of asukamycin, Streptomyces nodosus ssp. asukaensis. Structural variations of manumycins lieonly in the diverse initiation of the 'upper' polyketide chain. Inactivation of the gene involved in the biosynthesis of cyclohexanecarboxylic acid (CHC) turned off the production of asukamycin in the mutant strain and allowed an increased production ofother manumycins with the branched end of the upper chain
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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