Sensitive detection of interferon-gamma with engineered proteins and surface plasmon resonance biosensor

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F11%3A00437424" target="_blank" >RIV/61388971:_____/11:00437424 - isvavai.cz</a>
Alternative codes found
RIV/86652036:_____/11:00437424 RIV/67985882:_____/11:00437424
Result on the web
<a href="http://dx.doi.org/10.1016/j.proeng.2011.12.231" target="_blank" >http://dx.doi.org/10.1016/j.proeng.2011.12.231</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.proeng.2011.12.231" target="_blank" >10.1016/j.proeng.2011.12.231</a>

Result language
angličtina
Original language name
Sensitive detection of interferon-gamma with engineered proteins and surface plasmon resonance biosensor
Original language description
We present a novel surface plasmon resonance (SPR) biosensor for detection of human interferon gamma (hIFNy), an important diagnostic marker for several infectious diseases. The biosensor employs engineered proteins derived from albumin binding domain (ABD) and selected with ribosome display to provide high affinity towards hIFNy. We demonstrate that the biosensor provides rapid, sensitive, and cost-effective platform for the detection of hIFN? and allows its detection at nanomolar levels both in bufferand diluted human plasma
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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