Surface plasmon resonance biosensor based on engineered proteins for direct detection of interferon-gamma in diluted blood plasma

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F12%3A00387101" target="_blank" >RIV/61388971:_____/12:00387101 - isvavai.cz</a>
Alternative codes found
RIV/86652036:_____/12:00387101 RIV/67985882:_____/12:00387101
Result on the web
<a href="http://dx.doi.org/10.1016/j.snb.2012.08.024" target="_blank" >http://dx.doi.org/10.1016/j.snb.2012.08.024</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.snb.2012.08.024" target="_blank" >10.1016/j.snb.2012.08.024</a>

Result language
angličtina
Original language name
Surface plasmon resonance biosensor based on engineered proteins for direct detection of interferon-gamma in diluted blood plasma
Original language description
We present a novel surface plasmon resonance (SPR) biosensor for direct detection of human interferon gamma (hIFN). The biorecognition elements for hIFNare engineered proteins derived from albumin binding domain (ABD). Two methods for the immobilizationof ABD are compared: covalent coupling and immobilization via streptavidin?biotin interaction. The developed biosensor provides rapid and sensitive platform for the detection of hIFN at subnanomolar levels both in buffer and diluted human plasma.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JB - Sensors, detecting elements, measurement and regulation
OECD FORD branch
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Project
<a href="/en/project/KAN200670701" target="_blank" >KAN200670701: Surface plasmon resonance biosensors and protein arrays for medical diagnostics</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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