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Novel "soft" biodegradable nanoparticles prepared from aliphatic based monomers as a potential drug delivery system

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F12%3A00376067" target="_blank" >RIV/61388971:_____/12:00376067 - isvavai.cz</a>

  • Alternative codes found

    RIV/61389013:_____/12:00376067

  • Result on the web

    <a href="http://dx.doi.org/10.1039/C2SM07247E" target="_blank" >http://dx.doi.org/10.1039/C2SM07247E</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/C2SM07247E" target="_blank" >10.1039/C2SM07247E</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Novel "soft" biodegradable nanoparticles prepared from aliphatic based monomers as a potential drug delivery system

  • Original language description

    Herein, the synthesis and characterization of a new aliphatic biodegradable copolyester named PBS/PBDL (poly(butylene succinate-co-butylene dilinoleate)) is reported. Surfactant-free, narrowly distributed, nanosized spherical particles (RH < 60 nm) havebeen produced from the biodegradable material by applying a single-step nanoprecipitation protocol. Their structure was characterized in detail by employing a variety of scattering techniques and transmission electron microscopy (TEM). Combined SLS and DLS measurements suggested that the nanoparticles comprise a porous core conferring a non-compact characteristic. Their porosity enables water to be entrapped which is responsible for their pronounced stability and relatively fast degradation as followedby size exclusion chromatography (SEC).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Soft Matter

  • ISSN

    1744-683X

  • e-ISSN

  • Volume of the periodical

    8

  • Issue of the periodical within the volume

    16

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    12

  • Pages from-to

    4343-4354

  • UT code for WoS article

    000302030200008

  • EID of the result in the Scopus database