Novel "soft" biodegradable nanoparticles prepared from aliphatic based monomers as a potential drug delivery system
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F12%3A00376067" target="_blank" >RIV/61388971:_____/12:00376067 - isvavai.cz</a>
Alternative codes found
RIV/61389013:_____/12:00376067
Result on the web
<a href="http://dx.doi.org/10.1039/C2SM07247E" target="_blank" >http://dx.doi.org/10.1039/C2SM07247E</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/C2SM07247E" target="_blank" >10.1039/C2SM07247E</a>
Alternative languages
Result language
angličtina
Original language name
Novel "soft" biodegradable nanoparticles prepared from aliphatic based monomers as a potential drug delivery system
Original language description
Herein, the synthesis and characterization of a new aliphatic biodegradable copolyester named PBS/PBDL (poly(butylene succinate-co-butylene dilinoleate)) is reported. Surfactant-free, narrowly distributed, nanosized spherical particles (RH < 60 nm) havebeen produced from the biodegradable material by applying a single-step nanoprecipitation protocol. Their structure was characterized in detail by employing a variety of scattering techniques and transmission electron microscopy (TEM). Combined SLS and DLS measurements suggested that the nanoparticles comprise a porous core conferring a non-compact characteristic. Their porosity enables water to be entrapped which is responsible for their pronounced stability and relatively fast degradation as followedby size exclusion chromatography (SEC).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Soft Matter
ISSN
1744-683X
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
16
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
4343-4354
UT code for WoS article
000302030200008
EID of the result in the Scopus database
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