Isoquercitrin: Pharmacology, toxicology, and metabolism
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F14%3A00433017" target="_blank" >RIV/61388971:_____/14:00433017 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15110/14:33149007
Result on the web
<a href="http://dx.doi.org/10.1016/j.fct.2014.03.018" target="_blank" >http://dx.doi.org/10.1016/j.fct.2014.03.018</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.fct.2014.03.018" target="_blank" >10.1016/j.fct.2014.03.018</a>
Alternative languages
Result language
angličtina
Original language name
Isoquercitrin: Pharmacology, toxicology, and metabolism
Original language description
The flavonoid isoquercitrin (quercetin-3-O-beta-D-glucopyranoside) is commonly found in medicinal herbs, fruits, vegetables and plant-derived foods and beverages. This article reviews the occurrence, preparation, bioavailability, pharmacokinetics, toxicology and biological activity of isoquercitrin and "enzymatically modified (alpha-glucosylated) isoquercitrin" (EMIQ). Pure isoquercitrin can now be obtained on a large scale by enzymatic rutin hydrolysis with alpha-L-rhamnosidase. Isoquercitrin has higher bioavailability than quercetin and displays a number of chemoprotective effects both in vitro and in vivo, against oxidative stress, cancer, cardiovascular disorders, diabetes and allergic reactions. Although small amounts of intact isoquercitrin can be found in plasma and tissues after oral application, it is extensively metabolized in the intestine and the liver
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Food and Chemical Toxicology
ISSN
0278-6915
e-ISSN
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Volume of the periodical
68
Issue of the periodical within the volume
JUN 2014
Country of publishing house
GB - UNITED KINGDOM
Number of pages
16
Pages from-to
267-282
UT code for WoS article
000337653000029
EID of the result in the Scopus database
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