Prevention of early cure of type 1 diabetes by intranasal administration of gliadin in NOD mice

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F14%3A00440707" target="_blank" >RIV/61388971:_____/14:00440707 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Prevention of early cure of type 1 diabetes by intranasal administration of gliadin in NOD mice

Original language description

Induction of long-term tolerance to beta-cell autoantigens has been investigated both in animal models and in human tpe 1 diabetes in order to prevent the disease. As it was found in this study, intranasal gliadin also rescued a fraction of prediabetic NOd mice. In conclusion, in. vaccination with gliadin, an environmental antigen with possible etiological influnce in T1D, may represent a novel, safer strategy for prevention or ven early cure of T1D.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EC - Immunology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

PLoS ONE

ISSN

1932-6203

e-ISSN

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Volume of the periodical

9

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

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UT code for WoS article

000336736200090

EID of the result in the Scopus database

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