Sugared biomaterial binding lectins: achievements and perspectives
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F16%3A00462996" target="_blank" >RIV/61388971:_____/16:00462996 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1039/c6bm00088f" target="_blank" >http://dx.doi.org/10.1039/c6bm00088f</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c6bm00088f" target="_blank" >10.1039/c6bm00088f</a>
Alternative languages
Result language
angličtina
Original language name
Sugared biomaterial binding lectins: achievements and perspectives
Original language description
Lectins, a distinct group of glycan-binding proteins, play a prominent role in the immune system ranging from pathogen recognition and tuning of inflammation to cell adhesion or cellular signalling. The possibilities of their detailed study expanded along with the rapid development of biomaterials in the last decade. The immense knowledge of all aspects of glycan-lectin interactions both in vitro and in vivo may be efficiently used in bioimaging, targeted drug delivery, diagnostic and analytic biological methods. Practically applicable examples comprise photoluminescence and optical biosensors, ingenious three-dimensional carbohydrate microarrays for high-throughput screening, matrices for magnetic resonance imaging, targeted hyperthermal treatment of cancer tissues, selective inhibitors of bacterial toxins and pathogen-recognising lectin receptors, and many others.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GC15-02578J" target="_blank" >GC15-02578J: Modified multivalent poly-N-acetyllactosamine glycans as novel ligands of human galectin-3</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomaterials Science
ISSN
2047-4830
e-ISSN
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Volume of the periodical
4
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
19
Pages from-to
1142-1160
UT code for WoS article
000380895500001
EID of the result in the Scopus database
2-s2.0-84979265950