Molecular epidemiology of Trichophyton quinckeanum - a zoophilic dermatophyte on the rise
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F18%3A00488958" target="_blank" >RIV/61388971:_____/18:00488958 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/ddg.13408" target="_blank" >http://dx.doi.org/10.1111/ddg.13408</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/ddg.13408" target="_blank" >10.1111/ddg.13408</a>
Alternative languages
Result language
angličtina
Original language name
Molecular epidemiology of Trichophyton quinckeanum - a zoophilic dermatophyte on the rise
Original language description
Background: Formerly only referred to as a subspecies (T. mentagrophytes var. quinckeanum), T. quinckeanum once again constitutes a distinct species according to the updated taxonomy of dermatophytes. nPatients and methods: During routine diagnostic tests conducted at the Mycology Laboratory, Molbis, Germany, between 11/2013 to 1/2017 (three years and three months), all specimens sent in were examined for T. quinckeanum. Molecular biology methods employed included: 1) DNA hybridization (PCR ELISA), 2) gene sequencing of the ITS region and TEF-1 alpha, and 3) in some cases, MALDI-TOF mass spectrometry. nResults: Overall, 62 strains of T. quinckeanum were found. Sixty-eight percent of patients were female, 43% were children and adolescents (<= 19 years of age). Cats were a frequent source of infection. Sequencing of all 62 strains revealed a concordance of 100 % with T. quinckeanum sequences contained in the NCBI database. Isolates analyzed by MALDI-TOF mass spectrometry showed specific spectra. nConclusions: In Germany, the zoophilic dermatophyte T. quinckeanum currently appears to be more prevalent than expected. T. quinckeanum strains were isolated from children and adults with dermatomycosis and tinea capitis. Sources of infection with T. quinckeanum include small rodents (mice), horses, and - remarkably commonly - cats. Given that unequivocal morphological identification of this dermatophyte is not always possible, molecular methods have to be employed in the diagnosis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/NV17-31269A" target="_blank" >NV17-31269A: Molecular epidemiology and identification improvement of dermatophytes in the Czech Republic</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JDDG
ISSN
1610-0379
e-ISSN
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Volume of the periodical
16
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
21-32
UT code for WoS article
000419640700004
EID of the result in the Scopus database
2-s2.0-85040232653