Gut microbiota: puppeteer of the host juvenile growth
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F18%3A00489196" target="_blank" >RIV/61388971:_____/18:00489196 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1097/MCO.0000000000000463" target="_blank" >http://dx.doi.org/10.1097/MCO.0000000000000463</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/MCO.0000000000000463" target="_blank" >10.1097/MCO.0000000000000463</a>
Alternative languages
Result language
angličtina
Original language name
Gut microbiota: puppeteer of the host juvenile growth
Original language description
Purpose of reviewThis review focuses on the recent discoveries about the impact of intestinal microbiota on mammalian host juvenile growth.Recent findingsIntestinal microbiota is a powerful modulator of many facets of multicellular host's physiology. Recent results from human field studies and animal research have clearly shown that not only the nutrition, but also the intestinal microbiota impacts host postnatal growth kinetics. Absence of microbiome leads to stunted growth in mammalian gnotobiotic models and changes in the composition of the intestinal microbiota can impact the postnatal growth kinetics both positively and negatively under normal nutritional conditions as well as in undernutrition. Strikingly, specific bacterial strains are able to interact with GH/IGF-1 somatotropic axis activity, thus directly impacting host juvenile development.SummaryIntestinal microbiota dictates the pace of host postnatal growth. This newly described role envisages that therapy with specific bacterial strains, together with re-nutritional strategies, might successfully alleviate the long-term sequelae of undernutrition during childhood in humans.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30105 - Physiology (including cytology)
Result continuities
Project
<a href="/en/project/GJ18-07015Y" target="_blank" >GJ18-07015Y: Dissecting the role of microbiota and specific bacterial strains in mouse juvenile growth under normal/poor nutritional conditions</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Opinion in Clinical Nutrition and Metabolic Care
ISSN
1363-1950
e-ISSN
—
Volume of the periodical
21
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
179-183
UT code for WoS article
000429435500007
EID of the result in the Scopus database
2-s2.0-85045183836