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Molecular Functionalization of Planar Nanocrystalline and Porous Nanostructured Diamond to Form an Interface with Newborn and Adult Neurons

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F19%3A00504644" target="_blank" >RIV/61388971:_____/19:00504644 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378271:_____/19:00504644 RIV/67985823:_____/19:00504644 RIV/68407700:21460/19:00339420

  • Result on the web

    <a href="https://doi.org/10.1002/pssb.201800424" target="_blank" >https://doi.org/10.1002/pssb.201800424</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/pssb.201800424" target="_blank" >10.1002/pssb.201800424</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Molecular Functionalization of Planar Nanocrystalline and Porous Nanostructured Diamond to Form an Interface with Newborn and Adult Neurons

  • Original language description

    This article examines the ability of newly developed nanostructured porous boron-doped diamond (BDD) to form an interface with neural cells and the role of molecular functionalization by a polymer on this interface. Due to its high stability, biocompatibility, and electrical properties, BDD is a promising material for construction of neuroelectrodes. Nanostructuring and an increase in the surface specific area can further improve the sensitivity and performance of such electrodes. Here, porous BDD prepared in a multistep diamond deposition on a porous template consisting of a polymer and electrospun SiO2 fibers is examined. This work shows that this new material is biocompatible and does not exhibit any cytotoxicity on fibroblast cell lines. Further, this work shows that porous BDD supports regeneration of newborn and adult neurons when functionalized with poly-L-lysine.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Physica Status Solidi B-Basic Solid State Physics

  • ISSN

    0370-1972

  • e-ISSN

  • Volume of the periodical

    256

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    9

  • Pages from-to

    1800424

  • UT code for WoS article

    000461236600009

  • EID of the result in the Scopus database

    2-s2.0-85059164245