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Fluorescence assay to predict activity of the glycopeptide antibiotics

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F19%3A00507230" target="_blank" >RIV/61388971:_____/19:00507230 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/19:10394481 RIV/00064165:_____/19:10394481

  • Result on the web

    <a href="http://dx.doi.org/10.1038/s41429-018-0120-5" target="_blank" >http://dx.doi.org/10.1038/s41429-018-0120-5</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s41429-018-0120-5" target="_blank" >10.1038/s41429-018-0120-5</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Fluorescence assay to predict activity of the glycopeptide antibiotics

  • Original language description

    Here, we describe a fluorescent assay developed to study competitive binding of the glycopeptide antibiotics to live bacteria cells. This assay demonstrated that the mechanism of action of the lipoglycopeptide antibiotics strongly depends on the hydrophobicity of the substitutes, with the best antibacterial activity of the glycopeptide antibiotics equally sharing properties of binding to D-Ala-D-Ala residues of the nascent peptidoglycan and to the membrane.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Antibiotics

  • ISSN

    0021-8820

  • e-ISSN

  • Volume of the periodical

    72

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    JP - JAPAN

  • Number of pages

    4

  • Pages from-to

    114-117

  • UT code for WoS article

    000456873400008

  • EID of the result in the Scopus database

    2-s2.0-85057614746