Clustered Core- and Pan-Genome Content on Rhodobacteraceae Chromosomes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F19%3A00508671" target="_blank" >RIV/61388971:_____/19:00508671 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12310/19:43899501
Result on the web
<a href="https://academic.oup.com/gbe/article/11/8/2208/5527758" target="_blank" >https://academic.oup.com/gbe/article/11/8/2208/5527758</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/gbe/evz138" target="_blank" >10.1093/gbe/evz138</a>
Alternative languages
Result language
angličtina
Original language name
Clustered Core- and Pan-Genome Content on Rhodobacteraceae Chromosomes
Original language description
In Bacteria, chromosome replication starts at a single origin of replication and proceeds on both replichores. Due to its asymmetric nature, replication influences chromosome structure and gene organization, mutation rate, and expression. To date, little is known about the distribution of highly conserved genes over the bacterial chromosome. Here, we used a set of 101 fully sequenced Rhodobacteraceae representatives to analyze the relationship between conservation of genes within this family and their distance from the origin of replication. Twenty-two of the analyzed species had core genes clustered significantly closer to the origin of replication with representatives of the genus Celeribacter being the most apparent example. Interestingly, there were also eight species with the opposite organization. In particular, Rhodobaca barguzinensis and Loktanella vestfoldensis showed a significant increase of core genes with distance from the origin of replication. The uneven distribution of low-conserved regions is in particular pronounced for genomes in which the halves of one replichore differ in their conserved gene content. Phage integration and horizontal gene transfer partially explain the scattered nature of Rhodobacteraceae genomes. Our findings lay the foundation for a better understanding of bacterial genome evolution and the role of replication therein.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/LO1416" target="_blank" >LO1416: Algatech plus</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Genome Biology and Evolution
ISSN
1759-6653
e-ISSN
—
Volume of the periodical
11
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
2208-2217
UT code for WoS article
000484266300013
EID of the result in the Scopus database
2-s2.0-85071707883