Addressing Nanomaterial Immunosafety by Evaluating Innate Immunity across Living Species

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F20%3A00537242" target="_blank" >RIV/61388971:_____/20:00537242 - isvavai.cz</a>

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202000598" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202000598</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/smll.202000598" target="_blank" >10.1002/smll.202000598</a>

Result language

angličtina

Original language name

Addressing Nanomaterial Immunosafety by Evaluating Innate Immunity across Living Species

Original language description

The interaction of a living organism with external foreign agents is a central issue for its survival and adaptation to the environment. Nanosafety should be considered within this perspective, and it should be examined that how different organisms interact with engineered nanomaterials (NM) by either mounting a defensive response or by physiologically adapting to them. Herein, the interaction of NM with one of the major biological systems deputed to recognition of and response to foreign challenges, i.e., the immune system, is specifically addressed. The main focus is innate immunity, the only type of immunity in plants, invertebrates, and lower vertebrates, and that coexists with adaptive immunity in higher vertebrates. Because of their presence in the majority of eukaryotic living organisms, innate immune responses can be viewed in a comparative context. In the majority of cases, the interaction of NM with living organisms results in innate immune reactions that eliminate the possible danger with mechanisms that do not lead to damage. While in some cases such interaction may lead to pathological consequences, in some other cases beneficial effects can be identified.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30102 - Immunology

Project

<a href="/en/project/LO1509" target="_blank" >LO1509: Prague infrastructure for structural biology and metabolomics II</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Small

ISSN

1613-6810

e-ISSN

—

Volume of the periodical

16

Issue of the periodical within the volume

21

Country of publishing house

DE - GERMANY

Number of pages

25

Pages from-to

2000598

UT code for WoS article

000529890100001

EID of the result in the Scopus database

2-s2.0-85084242272