Interaction between nanomaterials and the innate immune system across evolution
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00571675" target="_blank" >RIV/61388971:_____/23:00571675 - isvavai.cz</a>
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1111/brv.12928" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/brv.12928</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/brv.12928" target="_blank" >10.1111/brv.12928</a>
Alternative languages
Result language
angličtina
Original language name
Interaction between nanomaterials and the innate immune system across evolution
Original language description
Interaction of engineered nanomaterials (ENMs) with the immune system mainly occurs with cells and molecules of innate immunity, which are present in interface tissues of living organisms. Immuno-nanotoxicological studies aim at understanding if and when such interaction is inconsequential or may cause irreparable damage. Since innate immunity is the first line of immune reactivity towards exogenous agents and is highly conserved throughout evolution, this review focuses on the major effector cells of innate immunity, the phagocytes, and their major sensing receptors, Toll-like receptors (TLRs), for assessing the modes of successful versus pathological interaction between ENMs and host defences. By comparing the phagocyte- and TLR-dependent responses to ENMs in plants, molluscs, annelids, crustaceans, echinoderms and mammals, we aim to highlight common recognition and elimination mechanisms and the general sufficiency of innate immunity for maintaining tissue integrity and homeostasis.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30102 - Immunology
Result continuities
Project
<a href="/en/project/LO1509" target="_blank" >LO1509: Prague infrastructure for structural biology and metabolomics II</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biological Reviews
ISSN
1464-7931
e-ISSN
1469-185X
Volume of the periodical
98
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
28
Pages from-to
747-774
UT code for WoS article
000913971400001
EID of the result in the Scopus database
2-s2.0-85146339127