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Spontaneous and Induced Tumors in Germ-Free Animals: A General Review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F21%3A00542584" target="_blank" >RIV/61388971:_____/21:00542584 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11310/21:10440289

  • Result on the web

    <a href="https://www.mdpi.com/1648-9144/57/3/260" target="_blank" >https://www.mdpi.com/1648-9144/57/3/260</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/medicina57030260" target="_blank" >10.3390/medicina57030260</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Spontaneous and Induced Tumors in Germ-Free Animals: A General Review

  • Original language description

    Cancer, bacteria, and immunity relationships are much-debated topics in the last decade. Microbiome's importance for metabolic and immunologic modulation of the organism adaptation and responses has become progressively evident, and models to study these relationships, especially about carcinogenesis, have acquired primary importance. The availability of germ-free (GF) animals, i.e., animals born and maintained under completely sterile conditions avoiding the microbiome development offers a unique tool to investigate the role that bacteria can have in carcinogenesis and tumor development. The comparison between GF animals with the conventional (CV) counterpart with microbiome can help to evidence conditions and mechanisms directly involving bacterial activities in the modulation of carcinogenesis processes. Here, we review the literature about spontaneous cancer and cancer modeling in GF animals since the early studies, trying to offer a practical overview on the argument.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Medicina-Lithuania

  • ISSN

    1010-660X

  • e-ISSN

    1648-9144

  • Volume of the periodical

    57

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    LT - LITHUANIA

  • Number of pages

    17

  • Pages from-to

    260

  • UT code for WoS article

    000633827600001

  • EID of the result in the Scopus database

    2-s2.0-85103593898