Spontaneous and Induced Tumors in Germ-Free Animals: A General Review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F21%3A00542584" target="_blank" >RIV/61388971:_____/21:00542584 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/21:10440289
Result on the web
<a href="https://www.mdpi.com/1648-9144/57/3/260" target="_blank" >https://www.mdpi.com/1648-9144/57/3/260</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/medicina57030260" target="_blank" >10.3390/medicina57030260</a>
Alternative languages
Result language
angličtina
Original language name
Spontaneous and Induced Tumors in Germ-Free Animals: A General Review
Original language description
Cancer, bacteria, and immunity relationships are much-debated topics in the last decade. Microbiome's importance for metabolic and immunologic modulation of the organism adaptation and responses has become progressively evident, and models to study these relationships, especially about carcinogenesis, have acquired primary importance. The availability of germ-free (GF) animals, i.e., animals born and maintained under completely sterile conditions avoiding the microbiome development offers a unique tool to investigate the role that bacteria can have in carcinogenesis and tumor development. The comparison between GF animals with the conventional (CV) counterpart with microbiome can help to evidence conditions and mechanisms directly involving bacterial activities in the modulation of carcinogenesis processes. Here, we review the literature about spontaneous cancer and cancer modeling in GF animals since the early studies, trying to offer a practical overview on the argument.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Medicina-Lithuania
ISSN
1010-660X
e-ISSN
1648-9144
Volume of the periodical
57
Issue of the periodical within the volume
3
Country of publishing house
LT - LITHUANIA
Number of pages
17
Pages from-to
260
UT code for WoS article
000633827600001
EID of the result in the Scopus database
2-s2.0-85103593898