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Multiple Sclerosis and Microbiome

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F22%3A00556542" target="_blank" >RIV/61388971:_____/22:00556542 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064165:_____/22:10444023 RIV/00216208:11110/22:10444023

  • Result on the web

    <a href="https://www.mdpi.com/2218-273X/12/3/433" target="_blank" >https://www.mdpi.com/2218-273X/12/3/433</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/biom12030433" target="_blank" >10.3390/biom12030433</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Multiple Sclerosis and Microbiome

  • Original language description

    The composition of microbiota and the gut-brain axis is increasingly considered a factor in the development of various pathological conditions. The etiology of multiple sclerosis (MS), a chronic autoimmune disease affecting the CNS, is complex and interactions within the gut-brain axis may be relevant in the development and the course of MS. In this article, we focus on the relationship between gut microbiota and the pathophysiology of MS. We review the contribution of germ-free mouse studies to our understanding of MS pathology and its implications for treatment strategies to modulate the microbiome in MS. This summary highlights the need for a better understanding of the role of the microbiota in patients' responses to disease-modifying drugs in MS and disease activity overall.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    <a href="/en/project/NU20-04-00077" target="_blank" >NU20-04-00077: Microbiome, its role in effectiveness of immunomodulatory therapy and pathogenesis of MS.</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomolecules

  • ISSN

    2218-273X

  • e-ISSN

    2218-273X

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    10

  • Pages from-to

    87

  • UT code for WoS article

    000776025800001

  • EID of the result in the Scopus database