Recent Progress in the Production of Cyanide-Converting Nitrilases-Comparison with Nitrile-Hydrolyzing Enzymes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00571188" target="_blank" >RIV/61388971:_____/23:00571188 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21460/23:00365004
Result on the web
<a href="https://www.mdpi.com/2073-4344/13/3/500" target="_blank" >https://www.mdpi.com/2073-4344/13/3/500</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/catal13030500" target="_blank" >10.3390/catal13030500</a>
Alternative languages
Result language
angličtina
Original language name
Recent Progress in the Production of Cyanide-Converting Nitrilases-Comparison with Nitrile-Hydrolyzing Enzymes
Original language description
Nitrilases have a high potential for application in organic chemistry, environmental technology, and analytics. However, their industrial uses require that they are produced in highly active and robust forms at a reasonable cost. Some organic syntheses catalyzed by nitrilases have already reached a high level of technological readiness. This has been enabled by the large-scale production of recombinant catalysts. Despite some promising small-scale methods being proposed, the production of cyanide-converting nitrilases (cyanide hydratase and cyanide dihydratase) is lagging in this regard. This review focuses on the prospects of cyanide(di)hydratase-based catalysts. The current knowledge of these enzymes is summarized and discussed in terms of the origin and distribution of their sequences, gene expression, structure, assays, purification, immobilization, and uses. Progresses in the production of other nitrilase catalysts are also tackled, as it may inspire the development of the preparation processes of cyanide(di)hydratases.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20801 - Environmental biotechnology
Result continuities
Project
<a href="/en/project/GA22-06785S" target="_blank" >GA22-06785S: Free-cyanide determination: new approaches based on enzyme cascades</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Catalysts
ISSN
2073-4344
e-ISSN
2073-4344
Volume of the periodical
13
Issue of the periodical within the volume
3
Country of publishing house
CH - SWITZERLAND
Number of pages
18
Pages from-to
500
UT code for WoS article
000954124300001
EID of the result in the Scopus database
2-s2.0-85151534333