Microbiota as the unifying factor behind the hallmarks of cancer

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F23%3A00578527" target="_blank" >RIV/61388971:_____/23:00578527 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/23:10466860 RIV/00064165:_____/23:10466860
Result on the web
<a href="https://link.springer.com/article/10.1007/s00432-023-05244-6" target="_blank" >https://link.springer.com/article/10.1007/s00432-023-05244-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00432-023-05244-6" target="_blank" >10.1007/s00432-023-05244-6</a>

Result language
angličtina
Original language name
Microbiota as the unifying factor behind the hallmarks of cancer
Original language description
The human microbiota is a complex ecosystem that colonizes body surfaces and interacts with host organ systems, especially the immune system. Since the composition of this ecosystem depends on a variety of internal and external factors, each individual harbors a unique set of microbes. These differences in microbiota composition make individuals either more or less susceptible to various diseases, including cancer. Specific microbes are associated with cancer etiology and pathogenesis and several mechanisms of how they drive the typical hallmarks of cancer were recently identified. Although most microbes reside in the distal gut, they can influence cancer initiation and progression in distant tissues, as well as modulate the outcomes of established cancer therapies. Here, we describe the mechanisms by which microbes influence carcinogenesis and discuss their current and potential future applications in cancer diagnostics and management.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30204 - Oncology

Project
<a href="/en/project/NV19-03-00179" target="_blank" >NV19-03-00179: Fecal microbiota transplantation in cancer patients treated with checkpoint inhibitor therapy.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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