RIP-seq reveals RNAs that interact with RNA polymerase and primary sigma factors in bacteria
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F24%3A00582831" target="_blank" >RIV/61388971:_____/24:00582831 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G33__/24:N0000003 RIV/00216224:90242/24:00139162 RIV/00216208:11130/24:10477339 RIV/00216208:11310/24:10477339
Result on the web
<a href="https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae081/7606967?login=true" target="_blank" >https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae081/7606967?login=true</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/nar/gkae081" target="_blank" >10.1093/nar/gkae081</a>
Alternative languages
Result language
angličtina
Original language name
RIP-seq reveals RNAs that interact with RNA polymerase and primary sigma factors in bacteria
Original language description
Bacteria have evolved structured RNAs that can associate with RNA polymerase (RNAP). Two of them have been known so far-6S RNA and Ms1 RNA but it is unclear if any other types of RNAs binding to RNAP exist in bacteria. To identify all RNAs interacting with RNAP and the primary σ factors, we have established and performed native RIP-seq in Bacillus subtilis, Corynebacterium glutamicum, Streptomyces coelicolor, Mycobacterium smegmatis and the pathogenic Mycobacterium tuberculosis. Besides known 6S RNAs in B. subtilis and Ms1 in M. smegmatis, we detected MTS2823, a homologue of Ms1, on RNAP in M. tuberculosis. In C. glutamicum, we discovered novel types of structured RNAs that associate with RNAP. Furthermore, we identified other species-specific RNAs including full-length mRNAs, revealing a previously unknown landscape of RNAs interacting with the bacterial transcription machinery.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nucleic Acids Research
ISSN
0305-1048
e-ISSN
1362-4962
Volume of the periodical
52
Issue of the periodical within the volume
May 8
Country of publishing house
US - UNITED STATES
Number of pages
23
Pages from-to
4604-4626
UT code for WoS article
001160557000001
EID of the result in the Scopus database
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