IN SITU T-CELL RESPONSES TO INFLUENZA ANDBORDETELLA PERTUSSIS INFECTIONS

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F24%3A00602176" target="_blank" >RIV/61388971:_____/24:00602176 - isvavai.cz</a>
Alternative codes found
RIV/68378050:_____/24:00602176
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/48/87" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/48/87</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
IN SITU T-CELL RESPONSES TO INFLUENZA ANDBORDETELLA PERTUSSIS INFECTIONS
Original language description
The upper respiratory tract (URT) is a site of entry for many public health-concerning pathogens such as SARS-CoV-2 (ref.1),the Influenza virus2, or Bordetella pertussis3. Although the URT represents an important site for the initiation and transmission of the infection, understanding the site-specific immunity in the nasal tissue during different infections is limited. So far, most works focused on respiratory infections have been concerned only with the lower respiratory tract (LRT)2. The adaptive immune system of URT consists of nasal-associated lymphoid tissue, which is a highly organized lymphoid structure with T and B cell areas and dispersed Tissue-resident memory T cells (Trm). Trm cells are a subset of memory T cells, which reside in non-lymphoid tissues, where they can act as alarm sensors in the immune surveillance network or as cytotoxic cells. Due to their advantageous location, they can be part of the first line of defense against many infections. The mechanism of development and the diversity and function of Trm cells are not yet completely understood.
Czech name
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Czech description
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Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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