Nanoparticles with Embedded Porphyrin Photosensitizers for Photooxidation Reactions and Continuous Oxygen Sensing

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388980%3A_____%2F17%3A00480025" target="_blank" >RIV/61388980:_____/17:00480025 - isvavai.cz</a>

Alternative codes found

RIV/61388955:_____/17:00480025 RIV/00216208:11310/17:10366655

Result on the web

<a href="http://dx.doi.org/10.1021/acsami.7b12009" target="_blank" >http://dx.doi.org/10.1021/acsami.7b12009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acsami.7b12009" target="_blank" >10.1021/acsami.7b12009</a>

Result language

angličtina

Original language name

Nanoparticles with Embedded Porphyrin Photosensitizers for Photooxidation Reactions and Continuous Oxygen Sensing

Original language description

We report the synthesis and characterization of sulfonated polystyrene nanoparticles (average diameter 30 +/- 14 nm) with encapsulated 5,10,15,20-tetraphenylporphyrin or ionically entangled tetracationic 5,10,15,20-tetralcis(N-methylpyridinium-4-yl)-porphyrin, their photooxidation properties, and the application of singlet oxygen-sensitized delayed fluorescence (SODF) in oxygen sensing. Both types of nanoparticles effectively photogenerated singlet oxygen, O-2((1)Delta(g)). The O-2((1)Delta(g)) phosphorescence, transient absorption of the porphyrin triplet states, and SODF signals were monitored using time-resolved spectroscopic techniques. The SODF intensity depended on the concentration of the porphyrin photosensitizer and dissolved oxygen and on the temperature. After an initial period (a few microseconds), the kinetics of the SODF process can be approximated as a monoexponential function, and the apparent SODF lifetimes can be correlated with the oxygen concentration. The oxygen sensing based on SODF allowed measurement of the dissolved oxygen in aqueous media in the broad range of oxygen concentrations (0.2-38 mg L-1). The ability of both types of nanoparticles to photooxidize external substrates was predicted by the SODF measurements and proven by chemical tests. The relative photooxidation efficacy was highest at a low porphyrin concentration, as indicated by the highest fluorescence quantum yield (Phi(F)), and it corresponds with negligible inner filter and self-quenching effects. The photooxidation abilities were sensitive to the influence of temperature on the diffusion and solubility of oxygen in both polystyrene and water media and to the rate constant of the O-2((1)Delta(g)) reaction with a substrate. Due to their efficient photogeneration of cytotoxic O-2((1)Delta(g)) at physiological temperatures and their oxygen sensing via SODF, both types of nanoparticles are promising candidates for biomedical applications.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10402 - Inorganic and nuclear chemistry

Project

<a href="/en/project/GA16-15020S" target="_blank" >GA16-15020S: Photoactive Polymer Materials with Nanostructured Surfaces for Biomedical Applications</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

ACS Applied Materials and Interfaces

ISSN

1944-8244

e-ISSN

—

Volume of the periodical

9

Issue of the periodical within the volume

41

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

36229-36238

UT code for WoS article

000413503700075

EID of the result in the Scopus database

2-s2.0-85031725427