The role of (HCO3)− ions in SBF on the interaction with bioactive glass-ceramic scaffold

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388980%3A_____%2F23%3A00568299" target="_blank" >RIV/61388980:_____/23:00568299 - isvavai.cz</a>

Alternative codes found

RIV/46747885:24620/23:00012078

Result on the web

<a href="https://doi.org/10.1016/j.mtchem.2022.101367" target="_blank" >https://doi.org/10.1016/j.mtchem.2022.101367</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mtchem.2022.101367" target="_blank" >10.1016/j.mtchem.2022.101367</a>

Result language

angličtina

Original language name

The role of (HCO3)− ions in SBF on the interaction with bioactive glass-ceramic scaffold

Original language description

Simulated Body Fluid (SBF) has concentrations of inorganic elements nearly equal to those of human blood plasma (BP). However, there are some differences between SBF and BP which can distort the results of in vitro bioactivity tests. Contrary to BP, SBF has a too low concentration of (HCO3)- ions (only 4 instead of 27 mmol·dm−3) and on the contrary a higher concentration of Cl− ions (introduced by the TRIS-HCl buffer). Indeed, the main difference between SBF and BP is the presence of the TRIS buffer in SBF which is used for neutral pH maintaining. The aim of this work was to study the effect of (HCO3)- ions in non-buffered SBF on the solubility of a bioactive glass-ceramic material and the formation of a new phase on the sample surface. A highly reactive glass-ceramic scaffold derived from 45S5 bioactive glass was tested under static-dynamic conditions using SBF solution with different (HCO3)- ion concentrations (4, 20 and 27 mmol·dm−3). The results were compared with data obtained using standardized buffered SBF solution. A non-buffered SBF solution with a concentration of (HCO3)- ions closer to the real concentration in BP was shown to have the potential to replace the standardized SBF solution since the ISO 23317:2014 using SBF can give false-positive results of in vitro bioactivity tests.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10402 - Inorganic and nuclear chemistry

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Materials Today Chemistry

ISSN

2468-5194

e-ISSN

2468-5194

Volume of the periodical

28

Issue of the periodical within the volume

MAR

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

101367

UT code for WoS article

000925565100001

EID of the result in the Scopus database

2-s2.0-85147004064