Remodelling of living bone induced by dynamic loading and drug delivery?Numerical modelling and clinical treatment

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388998%3A_____%2F10%3A00343142" target="_blank" >RIV/61388998:_____/10:00343142 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21220/10:00158919 RIV/68407700:21340/10:00158919
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Remodelling of living bone induced by dynamic loading and drug delivery?Numerical modelling and clinical treatment
Original language description
The biomechanical remodelling process is well formulated for bones and is divided into three stages: (1) bone resorption based on the osteoclast activity, (2) bone deposition based on the osteoblast activity and (3) bone growth control established on RANK/RANKL/OPG pathway-RANKL/OPG balance. The main driving force of remodelling process is a dynamic loading (cyclic compression and expansion, e.g. walking or running), which strongly influences the rate of chemical reactions. The evolution from the omogeneous density distribution to the corticalis and cancellous bone formation is shown. An inevitable influence of a dynamic mechanical loading and osteoprotegerin (OPG) concentration is demonstrated.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BJ - Thermodynamics
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)