High frequency ultrasound assesses transient changes in cartilage under osmotic loading
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388998%3A_____%2F20%3A00537892" target="_blank" >RIV/61388998:_____/20:00537892 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21340/20:00344684
Result on the web
<a href="http://www.aimspress.com/article/10.3934/mbe.2020281" target="_blank" >http://www.aimspress.com/article/10.3934/mbe.2020281</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3934/mbe.2020281" target="_blank" >10.3934/mbe.2020281</a>
Alternative languages
Result language
angličtina
Original language name
High frequency ultrasound assesses transient changes in cartilage under osmotic loading
Original language description
High-frequency ultrasound is used in this study to measure noninvasively, by means of osmotic loading, changes in speed of sound and cartilage thickness caused by variations of the salt concentration in the external bath. Articular cartilage comprises three main structural components: Water, collagen fibrils and proteoglycan macromolecules carrying negative charges. The negatively charged groups of proteoglycans attract cations and water into tissue and govern its shrinkage/swelling behavior, which is a fundamental mechano-electrochemical function of cartilage tissue. In this study, the mechano-electrochemical behavior of cartilage is modeled by a diffusion model. The proposed model enables simulations of cartilage osmotic loading under various parameter settings and allows to quantify cartilage mechanical properties. This theoretical model is derived from the kinetic theory of diffusion. The objectives of the study are to quantify time dependent changes in cartilage thickness, and in speed of sound within tissue with help of the finite element based simulations and data from experiments. Experimental data are obtained from fresh and trypsinized ovine patella samples. Results show that the proposed diffusion model is capable to describe transient osmotic loading of cartilage. Mean values and their deviations of the relative changes of cartilage characteristics in response to chemical loading are presented.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30304 - Public and environmental health
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Mathematical Biosciences and Engineering
ISSN
1547-1063
e-ISSN
—
Volume of the periodical
17
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
22
Pages from-to
5190-5211
UT code for WoS article
000573692900006
EID of the result in the Scopus database
2-s2.0-85093360017