The combined impact of tissue heterogeneity and fixed charge for models of cartilage: the one-dimensional biphasic swelling model revisited
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F19%3A00332333" target="_blank" >RIV/68407700:21340/19:00332333 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/s10237-019-01123-7" target="_blank" >https://doi.org/10.1007/s10237-019-01123-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10237-019-01123-7" target="_blank" >10.1007/s10237-019-01123-7</a>
Alternative languages
Result language
angličtina
Original language name
The combined impact of tissue heterogeneity and fixed charge for models of cartilage: the one-dimensional biphasic swelling model revisited
Original language description
Articular cartilage is a complex, anisotropic, stratified tissue with remarkable resilience and mechanical properties. It has been subject to extensive modelling as a multiphase medium, with many recent studies examining the impact of increasing detail in the representation of this tissue's fine scale structure. However, further investigation of simple models with minimal constitutive relations can nonetheless inform our understanding at the foundations of soft tissue simulation. Here, we focus on the impact of heterogeneity with regard to the volume fractions of solid and fluid within the cartilage. Once swelling pressure due to cartilage fixed charge is also present, we demonstrate that the multiphase modelling framework is substantially more complicated, and thus investigate this complexity, especially in the simple setting of a confined compression experiment. Our findings highlight the importance of locally, and thus heterogeneously, approaching pore compaction for load bearing in cartilage models, while emphasising that such effects can be represented by simple constitutive relations. In addition, simulation predictions are observed for the sensitivity of stress and displacement in the cartilage to variations in the initial state of the cartilage and thus the details of experimental protocol, once the tissue is heterogeneous. These findings are for the simplest models given only heterogeneity in volume fractions and swelling pressure, further emphasising that the complex behaviours associated with the interaction of volume fraction heterogeneity and swelling pressure are likely to persist for simulations of cartilage representations with more fine-grained structural detail of the tissue.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10300 - Physical sciences
Result continuities
Project
<a href="/en/project/EF17_050%2F0008025" target="_blank" >EF17_050/0008025: International Mobility of Researchers ? MSCA-IF in CTU</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomechanics and Modeling in Mechanobiology
ISSN
1617-7959
e-ISSN
1617-7940
Volume of the periodical
18
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
953-968
UT code for WoS article
000475703900006
EID of the result in the Scopus database
2-s2.0-85061215775