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DNA radiolysis in DNA-protein complex: a stochastic simulation of attack by hydroxyl radicals.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F03%3A49035188" target="_blank" >RIV/61389005:_____/03:49035188 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DNA radiolysis in DNA-protein complex: a stochastic simulation of attack by hydroxyl radicals.

  • Original language description

    The paper presents an improved version of model Radack, a stochastic simulation procedure of radiolytic attack to DNA that takes into account the reactivity of each amino acid of a specifically bound protein with hydroxyl radicals. The model is applied to the natural lactose operator-repressor complex taking advantage of crystallography- and NMR-based structures recently reported in the PDB databank. The putative modeled structures of a natural lactose operator - repressor complex are discussed.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/IAA1048103" target="_blank" >IAA1048103: Radiation induced damage of DNA - protein complexes</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2003

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Radiation Biology

  • ISSN

    0955-3002

  • e-ISSN

  • Volume of the periodical

    79

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    385-391

  • UT code for WoS article

  • EID of the result in the Scopus database