Nuclear reactions for protontherapy intensification
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F21%3A00539438" target="_blank" >RIV/61389005:_____/21:00539438 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.nimb.2020.11.002" target="_blank" >https://doi.org/10.1016/j.nimb.2020.11.002</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.nimb.2020.11.002" target="_blank" >10.1016/j.nimb.2020.11.002</a>
Alternative languages
Result language
angličtina
Original language name
Nuclear reactions for protontherapy intensification
Original language description
This paper presents some experimental results about the Li-7, B-11 and F-19 (p, alpha) nuclear reactions developed using proton beams at energy below 3 MeV in order to be applied to protontherapy. The energy released by proton beams during radiotherapy acts mainly at the end of the proton path in the biological medium, where it increases at high density inside the tumor. At this depth, it is possible to inject in the tumor compounds containing Li, B and F to generate energetic alpha particles from nuclear reactions. At the proton Bragg peak position it is possible to produce 1-8 MeV alpha particles, which enhance the energy density deposited in the tumor increasing the probability to damage the cells. Thanks to the higher relative biological efficiency of the alpha particles with respect to protons, it is expected that the alpha synergic particles defeat the tumor at lower doses.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10304 - Nuclear physics
Result continuities
Project
<a href="/en/project/GA19-02482S" target="_blank" >GA19-02482S: Ion beam writing synthesis of novel microstructures in advanced polymers and nanocomposites</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nuclear Instruments & Methods in Physics Research Section B
ISSN
0168-583X
e-ISSN
1872-9584
Volume of the periodical
486
Issue of the periodical within the volume
JAN
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
9
Pages from-to
28-36
UT code for WoS article
000595666300005
EID of the result in the Scopus database
2-s2.0-85095966842